IBUPROFEN DENK 400mg 100s TABLET(BOX)

Description:

• 400 mg  ibuprofen
• Breakable tablet for dosage flexibility
• Lower risk of gastrointestinal toxicity and cardiovascular side effects than other NSAID`s
• For use in acute pain, inflammation and fever
• Gluten- and lactose-free

Uses / Indications:

It is used for symptomatic treatment of mild to moderate pain including migraine headache. It is used for symptomatic treatment of pain and inflammation in arthritic diseases (e.g. rheumatoid arthritis) degenerative arthritic conditions (e.g. osteoarthritis), and in painful swelling and inflammation after soft tissue injuries.

Pregnancy interaction:

Inhibition of prostaglandin synthesis may adversely affect the pregnancy and/or the embryo/foetal development.

Side Effects:

Common side effects are headache, somnolence, vertigo, fatigue, agitation, dizziness, insomnia, irritability, gastrointestinal disorders, such as heartburn, dyspepsia, abdominal pain and nausea, vomiting, flatulence, diarrhoea, constipation, gastrointestinal ulcers, sometimes with bleeding and perforation (see section 4.4), occult blood loss which may lead to anaemia, melaena, haematemesis, ulcerative stomatitis, colitis, exacerbation of inflammatory bowel disease, complications of colonic diverticula (perforation, fistula).

How to use:

Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms. The maximum single dose for adults should not exceed 800 mg of ibuprofen. 200-400 mg given as a single dose or 3-4 times a day with an interval of 6 hours as required. The dosage in migraine headache should be: 400 mg given as a single dose, if necessary 400 mg with intervals up to 6 hours. The maximum daily dose should not exceed 1200 mg.

How it works:

Ibuprofen is a NSAID that possesses anti-inflammatory, analgesic and antipyretic activity. ibuprofen reduces pain possibly caused by inflammation or connected with it, swelling and fever. Ibuprofen exerts an inhibitory effect on prostaglandin synthesis by inhibiting the activity of cyclo-oxygenase. In addition ibuprofen has an inhibitory effect on ADP (adenosine diphosphate) or collagen stimulated platelet aggregation.